2021 Southern California Selections
All-Southern California
| Coach of the Year | ||||
| Jason Lynch | Saddleback | |||
| Most Valuable Player | ||||
| Garrett Duardo | Grossmont | |||
| First-Team | Second-Team | |||
| Garrett Duardo | Grossmont | Adam Dow * | Mt. San Antonio | |
| Konstainos Kouloues | Golden West | Niki Matheisen * | LA Valley | |
| Itamar Kolodny | Golden West | Dean Moody * | Cuesta | |
| Branabas Vidovics | Golden West | Hakap Ansuryan * | LA Valley | |
| Garrett Henderson | Golden West | Nikola Jancic * | Long Beach | |
| Andrew Barnevo | Saddleback | Ian Tauer * | Citrus | |
| Jack Stevens | Saddleback | Parker George * | Grossmont | |
| Nathan James | Saddleback | Felipe Ferriera | Golden West | |
| Emiliano Castro | Grossmont | Alec Isaacman | Saddleback | |
| Brock Kammerer | Grossmont | Austin Gaier | Grossmont | |
| Jacob Sill | Cuesta | Josh Halopoff | Cuesta | |
| Colton Boyd | Cuesta | Mario Vanzilotta | Cerritos | |
| Dane Howell | Orange Coast | Andre Galvez | Ventura | |
| Louis Grandi | Riverside | Ethan Pranajaya | Orange Coast | |
| Tommaso Baldinetti | Long Beach | Noah Stark | Mt. San Antonio | |
| Dominic Hernandez | Cerritos | Andrew Higginson | Golden West | |
| Carson Miller | San Diego Miramar | |||
| Tommy Dempsey | Riverside | |||
| Dylan Gallegos | Saddleback |
All of the first-team all-Southern California players and the top five (*) second-team players also receive All-American status.